Glyphosate Health Risks | Exposure to Roundup Linked to Cancer

Background on Roundup Weed Killer

Glyphosate, the active ingredient in Roundup, was first discovered to be an effective herbicide by Monsanto chemist John E. Franz in 1970.

The company introduced the chemical to the commercial market in 1976 and marketed it as a safe and effective herbicide under the brand name Roundup.

Monsanto heavily promoted Roundup as a “safe” and “environmentally friendly” herbicide, contributing to its widespread adoption and the eventual designation as the most widely used herbicide in the United States and globally.

Glyphosate works by inhibiting the EPSP synthase enzyme essential for plant growth.

Without this enzyme, plants cannot produce the proteins they need to grow and eventually die.

This mechanism of action made glyphosate effective in killing most types of plants.

The broad-spectrum herbicidal properties of Roundup made it a preferred choice for weed control in various settings.

Farmers utilized Roundup for its ability to increase crop yields, while homeowners found it convenient for maintaining lawns and gardens.

Roundup quickly became the most widely used herbicide in the world.

In the mid-1990s, Monsanto furthered its market dominance by introducing genetically modified (GM) crops that were resistant to glyphosate, dubbed “Roundup Ready” crops.

However, the widespread use of Roundup has raised concerns about the potential dangers of glyphosate on humans and the environment.

The historical promotion of Roundup by Monsanto has come under scrutiny following the International Agency for Research on Cancer’s (IARC) classification of glyphosate as a “probable human carcinogen” in 2015.

Many victims have come forward with complaints of the health effects of Roundup exposure, triggering a series of studies and legal actions.

Roundup and Glyphosate Health Risks

Because of the growing public concern about Roundup health risks, several scientific experts and organizations have conducted studies to investigate the potential dangers of glyphosate.

Researchers have explored its impact on animal and human health, considering both short-term and long-term effects.

While the findings of these studies have varied, many have linked glyphosate exposure to serious health problems.

In 2015, the International Agency for Research on Cancer (IARC), an agency under the World Health Organization (WHO), announced that glyphosate was a probable human carcinogen.

It classified the chemical under Group 2A, which means limited evidence of carcinogenicity in humans and sufficient evidence in experimental animals.

The International Agency for Research on Cancer (IARC) also discovered that exposure to the chemical could result in DNA and chromosomal damage in human cells.

This discovery was concerning because DNA damage can contribute to the development of various types of diseases, including cancer.

The Environmental Protection Agency (EPA) announced a different stance on the safety of glyphosate.

The agency maintains that glyphosate is unlikely to cause cancer in humans.

The EPA has argued that their dataset and studies, including 15 acceptable carcinogenicity research studies, are substantially more extensive and relevant to human health concerns than the IARC data.

The EPA believes that glyphosate residues in food and feed products are safe for consumption within established tolerance limits.

The agency’s evaluation primarily focuses on the risk associated with glyphosate residues in food and feed products, asserting that these are safe for consumption within established tolerance limits.

It’s important to note that the EPA’s assessment has been criticized for not adequately considering actual dermal or inhalation exposure to Roundup, which are common routes of exposure for agricultural workers and others who use the product regularly.

The Disagreement on Classifying Glyphosate as Carcinogenic to Humans

The disagreement between the US Environmental Protection Agency (EPA) and the International Agency for Research on Cancer (IARC) over the carcinogenicity of glyphosate-based herbicides (GBHs) stems from differing evaluations of genotoxicity data.

While the EPA concluded glyphosate is “not likely to be carcinogenic to humans,” based primarily on registrant-commissioned studies, the IARC classified glyphosate as “probably carcinogenic to humans (Group 2A),” relying heavily on peer-reviewed studies.

A key difference in their conclusions lies in the types of studies each organization used; the EPA’s evaluation focused on unpublished regulatory studies, which were mostly negative, whereas the IARC considered a broader range of research, including studies on formulated products and glyphosate’s primary metabolite, AMPA.

This inclusion of peer-reviewed and formulated product studies makes the IARC’s evaluation potentially more relevant to real-world exposures and the risks faced by individuals using or coming into contact with GBHs.

Consequently, the IARC’s approach and conclusions may be more applicable to understanding the true health risks associated with glyphosate exposure, especially for those with occupational exposure to these herbicides.

Health Conditions Linked to Glyphosate

Exposure to glyphosate has been linked to a range of serious health risks.

Direct Roundup exposure can occur through direct skin contact or inhalation during application, affecting both occupational users and the general population using the weedkiller on their homes.

The health impacts of glyphosate exposure may not become apparent immediately, as there can be a latency period before symptoms or conditions develop, complicating the task of directly linking exposure to specific health outcomes.

Research and debates have focused on understanding the mechanisms through which glyphosate could contribute to these health problems, including its genotoxic potential and the disruption of certain biological pathways.

Various Types of Cancers

The Journal of the National Cancer Institute (JNCI) published a study on the causal link between glyphosate exposure and specific oxidative stress biomarkers.

Oxidative stress is a key driver of various cancers.

The study discovered that glyphosate exposure increased the risk of developing certain types of cancers:

• Non-Hodgkin’s Lymphoma (NHL): This type of blood cancer affects the lymphatic system, an essential part of the immune system. Research shows that glyphosate exposure can increase the risk of NHL by as much as 41%.
• Leukemia: This type of cancer affects the blood-forming cells in the bone marrow. The Global Glyphosate Study (GGS) revealed that rats exposed to low doses of glyphosate-based herbicides developed leukemia, with half of the leukemia-caused deaths occurring at an early age.
• Multiple Myeloma: This type of cancer affects the plasma cells in the bone marrow. An animal study in the American Association for Cancer Research (AACR) journals found that glyphosate exposure accelerates the progression of multiple myeloma in rats.

Reproductive Issues

Glyphosate exposure may also affect reproductive health and fetal development.

Several studies found that glyphosate exposure may alter the development of the female reproductive tract, ovarian follicles, and uterus.

This alteration could lead to adverse consequences on fertility and reproductive health.

Nervous System Disruptions

Glyphosate may induce neurotoxic effects, disrupting the nervous system’s normal functioning.

Research shows that the chemical can affect cell development by deregulating signaling pathways, which alters neuronal growth and myelination.

Aside from harming neurotransmission, glyphosate can also induce neuroinflammation, oxidative stress, and mitochondrial dysfunction.

Gastrointestinal Effects

Long-term exposure to glyphosate has also been linked to various gastrointestinal (GI) conditions.

In an animal study, rabbits that ingested low glyphosate doses (175 mg/kg/day) experienced diarrhea.

Researchers also observed gastrointestinal disturbances in rats exposed to large doses of glyphosate.

Developmental Effects

Exposure to glyphosate during pregnancy may also have developmental effects on the fetus, such as low birth weight.

Studies and reviews have suggested that prenatal and early life exposure to glyphosate could be associated with various developmental issues, such as alterations in birth outcomes and delays in developmental milestones.

While the body of evidence continues to grow, the exact implications of glyphosate on human development remain a subject of ongoing scientific investigation, underscoring the need for further research to clarify these potential risks.

Hepatic Effects

Several animal studies have also found a link between glyphosate exposure and liver damage.

Research has suggested that glyphosate can cause oxidative stress and changes in liver enzyme levels, pointing towards its potential to disrupt normal liver function.

Long-term exposure has been associated with liver damage, including fatty liver disease, highlighting the importance of understanding and mitigating the risks associated with glyphosate use to protect liver health.

Renal Effects

Individuals exposed to high levels of glyphosate, particularly agricultural workers and populations in areas with heavy use of glyphosate-based herbicides, may be at an increased risk of suffering kidney damage.

The mechanism behind these renal effects may involve glyphosate’s capacity to cause oxidative stress and inflammation, leading to impairment of kidney function.

This emerging evidence underscores the need for further investigation into the long-term renal health consequences of glyphosate exposure and the development of protective measures for those at risk.

Symptoms of Glyphosate Exposure

Exposure to glyphosate can lead to various symptoms depending on the level and method of exposure.

Those who come into contact with this chemical, whether through occupational use or accidental exposure, may experience a range of immediate and long-term health effects.

It is crucial to recognize these symptoms early to seek appropriate medical attention and mitigate potential health risks.

Below are some of the possible symptoms associated with Roundup exposure:

• Skin irritation and rashes
• Eye irritation, including redness and burning
• Nausea and vomiting
• Diarrhea
• Sore throat and difficulty swallowing
• Respiratory problems, such as coughing and shortness of breath

Roundup Lawsuits are Still Being Filed

Thousands of individuals have filed lawsuits against Monsanto (now owned by Bayer AG), alleging that Roundup exposure caused their illnesses, particularly cancer.

Monsanto and Bayer AG have reached over 100,000 Roundup settlements, costing the companies $11 billion.

While this large number of lawsuits being settled is a good sign for plaintiffs, there are still pending Roundup cases, and no one knows how many Roundup lawsuits are yet to be filed.

Monsanto and Bayer AG still face over 40,000 pending cases, and many new victims are filing Roundup Lawsuits.

While there is no Roundup class action lawsuit, plaintiffs may file individual cases against the manufacturer or be considered to join the Roundup MDL.

Roundup MDL 2741 is currently in the United States District Court, Northern District of California, presided over by Judge Vince Chhabria.

Significant Roundup Settlements and Verdicts

Monsanto, now owned by Bayer, has faced significant financial repercussions due to jury verdicts and settlements related to the alleged link between its glyphosate-based herbicide, Roundup, and cancer, particularly Non-Hodgkin’s Lymphoma.

Roundup Lawsuits have led to Bayer paying out billions of dollars to settle claims, including a notable $10 billion settlement in 2020 to resolve current and potential future litigation.

These payouts reflect the growing legal and public health scrutiny over glyphosate’s safety and the company’s responsibility to consumers, further highlighting the controversy surrounding one of the world’s most widely used herbicides.

Some of the most notable Roundup lawsuit settlements to date include:

• In January 2024, a Philadelphia court ordered Bayer to pay $2.25 billion after jury concludes Roundup weed killer caused a man’s cancer.
• A San Francisco jury awarded $289 million in damages and $250 million in punitive damages to a groundskeeper who developed non-Hodgkin’s lymphoma in August 2018. A judge reduced the total amount to $78 million.
• Another plaintiff with NHL received $80 million in damages and $250 million in punitive damages in March 2019.
• In October 2023, Ernest Caranci received $175 million ($25 million in compensatory damages and $150 million in punitive damages) from a Philadelphia jury.

The June 2020 $10.9 billion settlement covered over 100,000 Roundup cases, and also established a $1.25 billion fund for future Roundup cancer claims, increasing it to $2 billion afterward.

What is the Role of Roundup Lawyers?

Individuals affected by glyphosate exposure often turn to Roundup cancer lawyers for representation.

Roundup lawyers provide legal counsel and representation to clients seeking compensation for their injuries.

They handle all aspects of the lawsuit, from filing to negotiation or trial.

Here are some crucial roles Roundup lawsuit lawyers play:

• Case Evaluation: Roundup cancer lawyers evaluate potential cases based on criteria such as medical records, diagnosis, exposure history, and severity of the illness.
• Filing Lawsuits: Roundup lawyers handle all the necessary paperwork and file lawsuits on behalf of their clients.
• Gathering Evidence: Lawyers gather evidence to support their client’s claim, including medical records, witness statements, expert opinions, and other relevant documents.
• Following Strict Deadlines: Lawsuits have strict deadlines, and Roundup lawyers ensure that all legal actions fall within the Roundup lawsuit statute of limitations.
• Negotiating Settlements: Most Roundup cases are settled before going to trial. Roundup attorneys deal with the manufacturer’s legal team to reach a fair settlement for their clients.
• Representing Clients in Court: If the parties cannot reach a fair settlement, the Roundup lawyer represents their clients in court and presents evidence to prove the manufacturer’s liability.
• Providing Legal Advice and Support: Roundup lawyers offer legal advice and support to their clients throughout the Roundup litigation. They also answer any questions and address any concerns their clients may have.

If you believe Roundup caused your non hodgkin lymphoma, contact our law firm.

You can also use the chatbot on this page to find out if you qualify for a potential Roundup Lawsuit.

Stay Informed and Seek Professional Advice

If you or a loved one has been exposed to glyphosate and developed health problems, stay informed about the ongoing Roundup litigation.

Reputable law firms and lawyers experienced in handling Roundup cases can provide you with the necessary legal advice and support.

It is incredibly to seek medical attention and retain all documentation related to medical treatment glyphosate exposure and cancer.

Your health and well-being should always be a top priority.

Having proper documentation can be essential in building a strong case if you decide to pursue legal action.

If you are considering filing a Roundup lawsuit, seek professional legal advice and make sure you understand your options thoroughly.

With the help of experienced Roundup lawyers, you may be able to seek compensation for health issues potentially caused by glyphosate exposure.

TorHoerman Law: Contact Our Roundup Lawyers Today

Roundup and glyphosate exposure may have severe consequences for human health.

If you or someone you know has been affected by glyphosate and is seeking legal representation, contact TorHoerman Law.

Our experienced Roundup lawyers have a proven track record of successfully representing clients in personal injury lawsuits.

We provide personalized and compassionate legal representation to help our clients seek justice and compensation for their injuries.

Contact us for a free consultation.

You can also use the chatbot on this page to find out if you qualify for the Roundup Cancer Lawsuit instantly.