Does Tylenol Cause Autism? New Study on Tylenol and Pregnancy Suggest Link

Research Linking Tylenol Use During Pregnancy to Increased Risk of Autism and Attention Deficit Hyperactivity Disorder

Acetaminophen is an active component in over a hundred medicines and OTC drugs that help treat pain and mild fever.

However, health professionals have long suspected a relationship between acetaminophen exposure during pregnancy and autism spectrum disorder (ASD).

New data from twenty-six epidemiological studies and dozens of animal studies suggest this may be the case.

Maternal-fetal medicine experts could no longer dismiss the human scientific evidence linking acetaminophen usage during pregnancy to ASD and attention deficit hyperactivity disorder, prompting the release of a consensus statement in 2021.

Here are some of the notable studies conducted by research that link Tylenol use and autism:

JAMA Pediatrics (2016): Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood

One notable study published in JAMA Pediatrics in 2016, conducted by researchers from the University of Bristol, analyzed data from the Avon Longitudinal Study of Parents and Children.

The study involved over 2,600 mother-child pairs and found that children exposed to acetaminophen in the womb had a higher risk of developing ASD and pregnancy complications by age seven.

The study suggested that the child’s risk increased with the frequency of Tylenol use during pregnancy.

Journal of Epidemiology (2016): Researchers Analyzed Data and Found a Clear Connection Between Acetaminophen Use by Pregnant Women and Neurodevelopment

The International Journal of Epidemiology published a study in 2016 that examined 2644 mother-child pairings.

Researchers analyzed data of children aged one and five to see if prenatal exposure to Tylenol increased their risk for autistic spectrum disorder or attention deficit hyperactivity disorder.

Autism risk was shown to be significantly higher when acetaminophen was used by pregnant women.

This was the first research to examine the relationship between Tylenol usage and autism in relation to the amount of acetaminophen consumed by pregnant women.

Johns Hopkins University Boston Birth Cohort (2019): Increased Acetaminophen Levels in Umbilical Blood Are Associated With an Increased Risk of ASD

A 2019 study by the Johns Hopkins University Boston Birth Cohort published in JAMA Psychiatry identified “dose-response” associations between prenatal acetaminophen exposure and an elevated risk of autism spectrum disorder and ADHD in cord biomarkers (blood samples taken from the umbilical cord).

In other words, higher acetaminophen levels in cord blood samples correlate with a higher prevalence of autism or ADHD diagnosis.

This further proved that using acetaminophen during pregnancy may be risky.

The study spanned twenty years, where researchers analyzed umbilical cord blood samples from 996 newborns and assessed biomarkers for acetaminophen levels.

Researchers found that newborns whose umbilical cord blood contained the most acetaminophen were three times more likely to develop autism spectrum disorder or ADHD than infants whose cord blood had the least.

Furthermore, the study demonstrated a consistent connection between acetaminophen levels within blood samples and autism spectrum disorder and childhood ADHD, even after controlling for potential confounding factors such as preterm birth, smoking, substance abuse, maternal stressors, and maternal body mass index.

The dose-response data suggests that Tylenol may alter fetal development.

This provides substantial support for a causal relationship with adverse neurodevelopmental outcomes.

The only real issue with this study is that it relied only on self-reporting by mothers, which isn’t foolproof.

Ethical considerations prevent researchers from going beyond observational studies of pregnant women.

Deliberately exposing pregnant people to a public health risk is unethical.

The limitations of this research include the possibility of recall bias and the absence of objective methods to determine when in-utero exposure to acetaminophen pain medicines occurred.

This means there was no systematic way to monitor how much Tylenol a pregnant woman consumed.

European Journal of Epidemiology (2021): Statistical Evidence Linking Tylenol Use to Increased Risk of Autism

Research on the effects of generic acetaminophen on developing fetuses and infants was published in the European Journal of Epidemiology, and it evaluated data from 73,881 children from six previous studies.

Data from the studies showed that the prevalence of ASD and ADHD diagnoses in children exposed to Tylenol or acetaminophen products during pregnancy was significantly higher than in children who were not.

Possible Mechanisms: Exploring the Link Between Tylenol and Autism

While the precise mechanisms underlying the potential link between Tylenol use during pregnancy and autism development are not fully understood, several hypotheses have been proposed.

One hypothesis suggests that Tylenol’s active ingredient, acetaminophen, may interfere with child development and functioning of the fetal brain.

Acetaminophen is known to reduce pain and fever by inhibiting the production of prostaglandins, which are involved in various physiological processes, including neurodevelopment.

It is speculated that the disruption of prostaglandin pathways during critical periods of fetal brain development may contribute to the increased risk of autism.

Another possible reason involves acetaminophen’s impact on oxidative stress and inflammation.

Acetaminophen affects the balance of antioxidants and reactive oxygen species in the body.

Excessive oxidative stress and inflammation during prenatal development have been associated with neurodevelopmental disorders, including autism.

It is possible that acetaminophen use during pregnancy could disrupt the delicate balance of oxidative stress and inflammation, potentially influencing the risk of autism in susceptible individuals.

However, it is essential to note that these hypotheses are speculative, and more research is needed to validate and elucidate these mechanisms.

The complex nature of autism development involves a combination of genetic, environmental, and epigenetic factors, making it challenging to pinpoint a single causal factor.

Aside from this, only limited medical alternatives exist.

Tylenol Autism Lawsuit Overview

The potential link between Tylenol use during pregnancy and an increased risk of autism has sparked legal action.

Several lawsuits have been filed against the manufacturers of generic acetaminophen by parents who believe their children’s autism was caused by prenatal exposure to the drug.

These Tylenol lawsuits allege that drug manufacturers failed to adequately warn pregnant people about the potential pregnancy risks associated with Tylenol.

The Tylenol plaintiffs argue that if they had been aware of the possible link, they would have made different choices regarding pain relief during pregnancy.

The legal process surrounding these acetaminophen lawsuits involves several stages, including filing complaints, discovery, pretrial proceedings, and potential trials.

Assessing Damages in a Tylenol Lawsuit

In acetaminophen autism lawsuits, damages typically aim to compensate the plaintiff for the harm or losses they have suffered as a result of the defendant’s actions.

In the context of a Tylenol lawsuit, if a plaintiff successfully demonstrates a causal connection between Tylenol use during pregnancy and the development of autism in their child, they may seek compensation for the following types of damages:

Medical Expenses

The plaintiff may seek reimbursement for the costs associated with diagnosing, treating, and managing the child’s autism.

This could include expenses for evaluations, therapy, medication, and specialized services.

Emotional Distress

The psychological impact on the parents and the child can be significant.

Damages may be sought for the emotional distress, pain and suffering, and loss of enjoyment of life experienced by the child and their family due to the child’s autism diagnosis.

Educational Expenses

Autism often requires specialized educational support and services.

The plaintiff may seek compensation for the costs of obtaining appropriate educational resources, including special education programs, therapy services, and adaptive equipment.

Caregiver Expenses

If the child requires additional caregiving or assistance due to autism, the plaintiff may seek compensation for the expenses associated with hiring caregivers or modifying the home environment to accommodate the child’s needs.

Permanent Disability

Permanent disability refers to a condition that substantially impairs an individual’s ability to perform essential life functions and activities.

If the child’s autism is determined to be a permanent disability that significantly restricts their daily functioning and independence, compensation for permanent disability may be sought.

This could include financial compensation to account for the ongoing care, support, and services needed to manage the disability.

Determining the amount of compensation for loss of enjoyment of life and permanent disability in a Tylenol autism lawsuit involves a thorough evaluation of the child’s specific circumstances.

Lawyers from TorHoerman Law have extensive experience reviewing Tylenol autism lawsuits and estimating fair compensation.

TorHoerman Law: Your Tylenol Autism Lawyers

TorHoerman Law has secured more than $4 billion in negotiated settlements and verdicts for personal injury lawsuits throughout its practice.

Our track record has earned us a reputation as some of the best personal injury lawyers in the country.

We are focused solely on competent legal representation, relationship building, and full financial recovery for your serious injuries.

Our law firm offers free, no-obligation case consultations for all potential clients.

If you or a loved one used Tylenol or Acetaminophen products during pregnancy, and your child was subsequently diagnosed with Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD), you may be eligible to file a Tylenol Autism ADHD Lawsuit.

Contact TorHoerman Law today to learn more about your legal options, or use the chatbot on this page to see if you qualify for a Tylenol Autism ADHD Lawsuit instantly.

TorHoerman Law: Your Tylenol Autism Lawyers